Cxc chemokine ligand-10
WebJul 29, 2011 · C–X–C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10 kDa (IP-10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family. CXCL10 binds CXCR3 receptor to induce chemotaxis, apoptosis, cell growth and angiostasis. WebApr 25, 2024 · The prognosis of pancreatic cancer is poor, with a 5-year survival rate of less than 10%. Studies have shown that chemokines in the tumour microenvironment are often altered, which is associated with immune infiltration and the prognosis and survival of pancreatic cancer patients. Multiomics and bioinformatics tools were used to clarify CXC …
Cxc chemokine ligand-10
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C-X-C motif chemokine ligand 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is an 8.7 kDa protein that in humans is encoded by the CXCL10 gene. C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family. See more The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. See more CXCL10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such … See more CXCL9, CXCL10 and CXCL11 have proven to be valid biomarkers for the development of heart failure and left ventricular dysfunction, suggesting an underlining … See more • Human C7 genome location and C7 gene details page in the UCSC Genome Browser. • Human CXCL10 genome location and See more The three-dimensional crystal structure of this chemokine has been determined under 3 different conditions to a resolution of up to 1.92 Å. The Protein Data Bank accession codes … See more Baseline pre-treatment plasma levels of CXCL10 are elevated in patients chronically infected with hepatitis C virus (HCV) of genotypes 1 or 4 who do not achieve a … See more • Farber JM (March 1997). "Mig and IP-10: CXC chemokines that target lymphocytes". Journal of Leukocyte Biology. 61 (3): 246–57. doi:10.1002/jlb.61.3.246. PMID 9060447 See more Web15-Deoxy-Δ 12,14,-prostaglandin J 2 inhibits IFN-inducible protein 10/CXC chemokine ligand 10 expression in human microglia : Mechanisms and implications. / Si, Qiusheng; Zhao, Meng Liang; Morgan, Anna C.A. et al. In: Journal of Immunology, Vol. 173, No. 5, 01.09.2004, p. 3504-3513. Research output: Contribution to journal › Article › peer ...
WebNational Center for Biotechnology Information WebThe chemokine receptor CCR5 is a drug target to prevent transmission of HIV/AIDS. We studied four analogs of the native chemokine regulated, on activation, normal T-cell-expressed, and secreted (RANT
WebThe CC chemokines have been renamed CC chemokine ligand (CCL) 1, 2, 3, etc., and the CXC chemokines, CXCL1, 2, etc. . In this paper, we use the new nomenclature but also provide the traditional name when introducing a new chemokine, as most workers in this field, including ourselves, will need some time to get used to the new nomenclature. WebDiscussion. In the above studies, we identified a chemokine, CXCL16, which represents the only CXC chemokine to date that exists in a transmembrane form. CXCL16 was expressed on T cell zone DCs ...
WebApr 11, 2014 · Chemokines were recognized originally for their ability to dictate the migration and activation of leukocytes. However, CXC chemokine ligand 12 (CXCL12, also …
WebHowever, the differential expression profiles, prognostic values, and specific mechanisms of the CXC chemokine family in LUAD have not been clarified. Methods: ... Spaks A, Svirina D, Spaka I, et al. CXC chemokine ligand 4 (CXCL4) is predictor of tumour angiogenic activity and prognostic biomarker in non-small cell lung cancer (NSCLC) patients ... credit one bank card phone numberWebDec 6, 2010 · Here we identify the chemokine CXCL10 as such a marker of progressive liver disease in patients undergoing transplantation for HCV; it is independent of other … credit one bank card loginWebCitokinski ligand 5 (C-X-C motiv) jest protein koji je kod ljudi kodiran genom CXCL5 ili ... CXCL5 je mali citokin u porodici CXC hemokina koji je također poznat ... et al. (1998). "Differential usage of the CXC chemokine receptors 1 and 2 by interleukin-8, granulocyte chemotactic protein-2 and epithelial-cell-derived neutrophil attractant-78 buckle for bow tieWebThe Quantikine Human IP-10 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human IP-10 in cell culture supernates, serum, plasma, saliva, and urine. It contains E. coli-expressed recombinant human IP-10 and has been shown to accurately quantitate the recombinant factor.Results obtained using natural human IP-10 showed … credit one bank card shippingcredit one bank card visaWebChemokine. Chemokines are a family of small cytokines, or proteins secreted by cells. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3 ... buckle forceWebMay 30, 2024 · CXC-chemokine receptor 3 (CXCR3) and its ligands CXC-chemokine ligand 9 (CXCL9) and CXCL10 have a key role in driving the trafficking of T H 1 cells, CD8 + T cells and NK cells into the tumour ... buckle forebear dynamo pediatrician