WebThe Hocek group currently consists of 3 staff scientists, 2 postdocs, 21 PhD students and several undergrad students. Group research interests: Novel types of modified derivatives and analogues of nucleobases, nucleosides, nucleotides and nucleic acids are designed and prepared for applications in all areas of biomedicinal sciences (medicinal ... WebHocek Lab. 334 likes · 48 talking about this. Michal Hocek research group http://hocekgroup.uochb.cas.cz
Impact of Cytosine 5-Halogens on the Interaction of DNA with ...
WebSynthetic modification of nucleoside structures provides access to molecules of interest as pharmaceuticals, biochemical probes, and models to study diseases. Covalent modification of the purine and pyrimidine bases is an important strategy for the synthesis of these adducts. Palladium-catalyzed cross-coupling is a powerful method to attach groups to the … WebOur group has been selected for membership in the Gilead Sciences Research Center 2016-2024 (GSRC-3). I am happy and grateful that the generous funding... Facebook goodway cleaning projectiles
Sensors Free Full-Text The Effects of Dithiothreitol on DNA
WebSep 2, 2024 · Modified nucleic acids, also called xeno nucleic acids (XNAs), offer a variety of advantages for biotechnological applications and address some of the limitations of first-generation nucleic acid therapeutics. Indeed, several therapeutics based on modified nucleic acids have recently been approved and many more are under clinical evaluation. … http://hocekgroup.uochb.cas.cz/members/menova.html WebAlthough our group is primarily not aiming at synthetic methodology development, we need to develop new methodologies and approaches for the synthesis of modified … goodway cleaner