Web24 jun. 2010 · Deleting TβRII in the Collecting System Worsens Renal Injury after UUO. To define the role of TβRII in development of the renal collecting system, we deleted TβRII at the initiation of UB development (embryonic day 10.5) by crossing the Tgfbr2 flox/flox mouse on a ROSA26 reporter background with the Hoxb7Cre mouse. Strong β-galactosidase … Web1 jan. 2024 · Based on the finding that the collecting system of the Hoxb7cre:Itga6 flox/flox and Hoxb7cre:Itgb4 flox/flox mice developed dysplastic papillae over time, we tested the hypothesis that α6-containing integrins play a critical role in maintaining kidney structure following injury by subjecting them to unilateral ureteric obstruction (UUO). ). These …
TAZ/Wnt-β-catenin/c-MYC axis regulates cystogenesis in …
WebWHAT TO EXPECT. A confirmation will be sent after order placement. Typically, eight or more animals are produced. The total number, sex and genotypes will be provided to you … WebMice with conditional deletion of fibroblast growth factor receptor 2 (Fgfr2) in the ureteric bud using a Hoxb7cre line (Fgfr2(UB-/-)) develop severe ureteric branching defects; … does haemophilus influenzae need isolation
β1-Integrin is required for kidney collecting duct morphogenesis …
Web25 mrt. 2015 · The collecting system of the kidney develops from the ureteric bud (UB), which undergoes branching morphogenesis, a process regulated by multiple factors, … Web12 okt. 2016 · Background Mutations in the tumor suppressor gene von Hippel-Lindau (VHL) underlie a hereditary cancer syndrome—VHL disease—and are also frequently observed … Web22 mrt. 2024 · Hoxb7Cre Rosa nT-nG/nT-nG generated nuclear GFP + kidney tubules and yielded living GFP +, calcein AM + cells upon FACS (Supplemental Figure 3). Compared with unsorted single cells prepared from the whole kidney, Hoxb7Cre Rosa nT-nG/nT-nG enriched collecting duct principal cell genes and depleted TALH, proximal tubule, and … does haf need to be repaid