WebWe analyzed levels of TFEB in liver tissues from patients with alcoholic hepatitis and from healthy donors (controls) by immunohistochemistry. Results: Liver tissues from mice on … Web15 May 2024 · This study was conducted to investigate the autophagic response of Sertoli cells (SCs) to acute ethanol toxicity using in vivo and in vitro models. Adult Wistar rats were intraperitoneally injected with either 5 g/kg ethanol or phosphate-buffered saline (for the control group) and sacrificed 0, 3, 6 and 24 h after injection. Compared to the control …
Bile duct neoplasm in TFEB-overexpressing liver. a Retrograde …
Web5 Sep 2024 · Trehalose, a disaccharide, activates TFEB and protects against diet-induced nonalcoholic fatty liver disease in mice. The aim of the present study was to investigate … Web17 Feb 2024 · For example, TFEB activates autophagy to indirectly inhibit liver steatosis and against weight gain in obesity (Zhang Y. et al., 2024). TFEB also contributes to being a … phoo phoo definition
TFEB at a glance - PMC - National Center for Biotechnology Information
Web6 May 2024 · TFEB in controlling liver cell fate during development and regeneration, which may also . contribute to the development of biliary cancer [80]. It als o sugge sted tha t the ex pressio n . Web21 Jul 2024 · Despite many target genes are similarly modulated by TFEB in different cell types, TFEB has been shown to have specialized functions in different tissues: in the liver, in addition to lysosomal function and autophagy, TFEB regulates genes important for the control of lipid metabolism, including lipophagy and fatty acid oxidation [ 20] [ 21 ]; in … WebDynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply Normal metabolism requires a controlled balance … phoo editing with gussian blur